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Please see https://merck.github.io/boxly/articles/ for the full documentation. Here is only a minimal example:

library("boxly")

meta_boxly(
  boxly_adsl,
  boxly_adlb,
  population_term = "apat",
  observation_term = "wk12",
  observation_subset = AVISITN <= 12 & !is.na(CHG)
) |>
  prepare_boxly() |>
  boxly()