Function reference • gsdmvn

All functions

ahr_blinded(): Blinded estimation of average hazard ratio

gridpts(): Grid points for group sequential design numerical integration

gridpts_(): Grid points for group sequential design numerical integration

gs_b(): gs_b: Default boundary generation

gs_bound(): Lower and Upper Bound of Group Sequential Design

gs_create_arm(): Create "npsurvSS" arm object

gs_design_ahr(): Group sequential design using average hazard ratio under non-proportional hazards

gs_design_combo(): Group sequential design using MaxCombo test under non-proportional hazards

gs_design_npe(): Group sequential design computation with non-constant effect and information

gs_design_nph(): Fixed and group sequential design under non-proportional hazards

gs_design_wlr(): Group sequential design using weighted log-rank test under non-proportional hazards

gs_info_ahr(): Information and effect size based on AHR approximation

gs_info_wlr(): Information and effect size for Weighted Log-rank test

gs_power_ahr(): Group sequential design power using average hazard ratio under non-proportional hazards

gs_power_combo(): Group sequential design power using MaxCombo test under non-proportional hazards

gs_power_npe(): Group sequential bound computation with non-constant effect

gs_power_nph(): Group sequential design power under non-proportional hazards

gs_power_wlr(): Group sequential design power using weighted log rank test under non-proportional hazards

gs_prob(): Group sequential boundary crossing probabilities

gs_prob_combo(): MaxCombo Group sequential boundary crossing probabilities

gs_spending_bound(): Derive spending bound for group sequential boundary

gs_spending_combo(): Derive spending bound for MaxCombo group sequential boundary

gsdmvn: gsdmvn: A package for group sequential design under non-proportional hazards (NPH)

h1(): Initialize numerical integration for group sequential design

h1_(): Initialize numerical integration for group sequential design

hupdate(): Update numerical integration for group sequential design

hupdate_(): Update numerical integration for group sequential design

pmvnorm_combo(): Multivariate Normal Distribution for Multivariate Maximum Statistics

wlr_weight_fh() wlr_weight_1() wlr_weight_n(): Weight Function of Weighted Log-rank Test